Christopher A. Ahern, Ph.D.

Associate Professor

Office: 4256 CBRB

Lab: 4256 CBRB

Phone: (319) 335-6964

Lab: (319) 335-6990

FAX: (319) 335-7330

Email: christopher-ahern@uiowa.edu

Web Site: Ahern Lab

Education and Other Appointments

  • 2002 - Ph.D., University of Wisconsin, Madison
  • 2002-2007 - Postdoc, Jefferson Medical College
  • 2008-2012 - Assistant Professor, Departments of Anesthesiology and Pharmacology and Therapeutics at the University of British Columbia

Research Interests

Our current research focus is on the function and pharmacology voltage-gated sodium channels that drive the rapid upstroke of the action-potential throughout the body. We find motivation in the observation that inherited or acquired functional defects in these integral membrane proteins is associated with cardiac arrhythmia, epilepsy, multiple sclerosis and painful syndromes. In the lab, we work at the interface of membrane biophysics and chemical biology. Our particular expertise is in the synthesis and expression channels harboring tailor made non-natural amino acids and the general application of chemical biological approaches to the study of voltage-gated channels. We have had success in expressing synthetic amino acids in many channel and receptor types for pharmacological studies of ligand and drug interactions as well as structure function relationships.

Selected Publications

Current Publications