Mark E. Anderson, M.D., Ph.D.

Professor of Medicine and Molecular Physiology & Biophysics

University of Minnesota, Stanford University

Research Interests

Dr. Anderson's clinical interests include devices and techniques such as pacemakers, defibrillators and catheter ablation that improve and rescue ailing hearts. His research interests lie in understanding the biology behind cardiac arrhythmias and using that knowledge to develop new therapies for this major cause of death in the United States. In particular, his research focuses on a signaling protein called calmodulin kinase II and the role it plays in heart rhythm abnormalities and heart muscle enlargement.

Selected Publications

1. Rong Zhang, Michelle S.C. Khoo, Yuejin Wu, Igor Dzhura, Gemin Ni, Tatiana A. Vishnivetskaya, Chad Grueter, Ernest C. Madu, Vsevolod V. Gurevich, Roger J. Colbran, Mark E. Anderson. Calmodulin kinase II inhibition protects against structural heart disease. Nature Medicine 2005, doi:10.1038/nm1215.

2. Rong Zhang, Igor Dzhura, Chad Grueter, William Thiel, Roger J. Colbran, Mark E. Anderson. A calmodulin responsive inter-subunit signaling complex determines L-type Ca 2+ channel gating. 2005, In press, FASEB J.

3. Michelle S.C. Khoo, Prince J. Kannankeril, Jingdong Li, Rong Zhang, Sabina Kupershmidt, Wei Zhang, James B. Atkinson, Roger J. Colbran, Dan M. Roden, Mark E. Anderson. Calmodulin kinase II activity is required for normal atrioventricular nodal conduction. 2005, In press, J Cardiac Electrophysiol.