Molecular Physiology & Biophysics University of Iowa Carver College of Medicine
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Faculty Profiles by Research Specialization

Cell and Molecular Biology

Michael Anderson
Genetic and molecular dissection of mechanisms contributing to ocular disease

Kevin Campbell
Cell Membrane Integrity and Muscular Dystrophy

Michael Henry
Molecular and cellular biology of cancer metastasis.

Wayne Johnson
Molecular mechanisms of sensory signal transduction

Scott Moye-Rowley
Molecular and cellular biology of eukaryotic stress resistance

Robert Piper
Genetic and biochemical analysis of cellular machinery controlling lysosome and endosome biogenesis

Andrew Russo
Control of neuronal gene expression involved in migraine

Deborah Segaloff
Folding and processing of G protein-coupled receptors

Mark Stamnes
Mechanisms of protein sorting and vesicular transport; mechanisms of cell structure assembly

Curt Sigmund
Transcriptional regulation of renin and angiotensinogen gene expression in transgenic mice; post-transcriptional regulation of renin expression

 

Signal Transduction

Nikolai Artemyev
Molecular mechanisms of sensory signal transduction; G-protein signaling systems; photoreceptors and visual transduction

Paul Rothman
JAK/STAT Signaling in normal and transformed cells

Deborah Segaloff
Molecular mechanisms of G protein coupled receptor signaling

Thomas Schmidt
Autoregulation of adrenocorticosteroid receptors; intracellular mode of action of glucocorticoid hormones; effects of immunosuppressive drugs on glucocorticoid receptor-mediated gene transcription

 

Neurobiology

Michael Anderson
Mechanisms contributing to glaucomatous neurodegeneration

Kevin Campbell
Cell Membrane Integrity and Muscular Dystrophy

Beverly Davidson
Neurodegenerative diseases and gene therapy to the central nervous system

Robert Fellows
Cellular and molecular actions of growth factors and hormones on development of cultured neurons and glia

N. Charles Harata
Structure and function of synapses in mammalian brains

Wayne Johnson
Sensory control of innate behaviors

Andrew Russo
Control of neuronal gene expression involved in migraine

 

Structure and Function of Membrane Ion Channels and Transporters

Francois Abboud
Function of stretch-activated channels and E-NaC/Degenerin proteins in nodose baroreceptor neurons; Modulation of Na+ and K+ channel activation in baroreceptor neurons by autocrine factors; Molecular mechanisms involved in K+ channel activation in baroreceptor neurons

Alessio Accardi
Molecular and structural underpinnings regulating the movement of charged ions across cellular membranes

Kevin Campbell
Cell Membrane Integrity and Muscular Dystrophy

Mark Chapleau
Molecular and cellular mechanisms that determine baroreceptors reflex sensitivity in normal and pathological states.

Sarah England
The role of K+ channels in regulation of vascular and uterine smooth muscle excitability

N. Charles Harata
Structure and function of synapses in mammalian brains

Wayne Johnson
Molecular mechanisms of mechanosensitive ion channel function

Peter Mohler

Erwin Shibata
Signal transduction of ion channels by membrane receptor activation; cardiac and smooth muscle electrophysiology

Peter Snyder
Structure, function, and regulation of DEG/ENaC ion channels, and their role in diseases such as hypertension

Michael Welsh
Structure and function of the cystic fibrosis transmembrane regulator chloride channel; Innate immunity in defense of the pulmonary airways; Gene therapy for lung diseases; Biology of ENaC sodium channels and their dysfunction in disease; Structure, function and physiology of nonvoltage-gated sodium channels with an emphasis on mechanosensation

 

Integrative Physiology

Francois Abboud
Mechanosensory function of baroreceptor neurons in blood pressure regulation

Michael Anderson
Pathophysiology of altered intraocular pressure regulation; Maintenance of ocular immune privilege

Kevin Campbell
Cell Membrane Integrity and Muscular Dystrophy

Mark Chapleau
Molecular and cellular mechanisms that determine baroreceptors reflex sensitivity in normal and pathological states.

Michael Henry
Vascular function and metastasis

Wayne Johnson
Sensory control of innate behaviors

Andrew Russo
Control of neuronal gene expression involved in migraine

Curt Sigmund
Molecular Genetics of Hypertension and Renin-Angiotensin System; Transgenic and Gene Targeting Models of Cardiovascular Disease; Integrated Cardiovascular Physiology in Transgenic Mice

 

   
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